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The automated cell count has largely replaced the“manual” cell count as an inexpensive, easy, and rapid wayto obtain information about the hematological system aswell as other organ systems.
(2007) Selective changes ofresting-state networks in individuals at risk for Alzheimer’s dis-ease. Further research demonstrated that an elevatedloading dose (600 mg) resulted in a more rapid inhibition ofplatelet function.108 Furthermore, clinical studies have confirmedthat the higher loading dose results in improved outcomes amongpatients undergoing percutaneous coronary intervention.110,130Additional studies have not demonstrated additional benefitfrom even higher loading doses of clopidogrel (900 mg) inthe setting of ACS.131,132 Current guidelines for percutaneouscoronary intervention now reflect this data and recommendthe higher loading dose (600 mg).52 Clinical trials have alsoexplored alternative maintenance doses for clopidogrel therapy.The CURRENT-OASIS 7 trial randomized 25,086 patients toreceive double-dose clopidogrel (600 mg followed by 150 mg for6 days) or standard dose clopidogrel (300 mg followed by 75 mgdaily). Upper endoscopy reveals no gastritis and no ulcer disease.
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